Three Classes of Genes Mutated In Colorectal Cancers with Chromosomal Instability
نویسندگان
چکیده
منابع مشابه
Three classes of genes mutated in colorectal cancers with chromosomal instability.
Although most colorectal cancers are chromosomally unstable, the basis for this instability has not been defined. To determine whether genes shown to cause chromosomal instability in model systems were mutated in colorectal cancers, we identified their human homologues and determined their sequence in a panel of colorectal cancers. We found 19 somatic mutations in five genes representing three ...
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ژورنال
عنوان ژورنال: Cancer Research
سال: 2004
ISSN: 0008-5472,1538-7445
DOI: 10.1158/0008-5472.can-04-0587